protein

Cathepsin K Protein, Mouse (His)

HY-P72157

5 μg;10 μg;20 μg;50 μg;100 μg

110;187;318;575;890 USD

Cathepsin K Protein, Mouse (His)

proteins

E. coli

5 μg;10 μg;20 μg;50 μg;100 μg

110;187;318;575;890 USD

Cathepsin K protein is a thiol protease that is critical in osteoclastic bone resorption and exhibits potent endoprotease activity against fibrinogen under acidic conditions. Its potential role in extracellular matrix degradation is noteworthy. Cathepsin K Protein, Mouse (His) is the recombinant mouse-derived Cathepsin K protein, expressed by E. coli , with N-6*His labeled tag. The total length of Cathepsin K Protein, Mouse (His) is 215 a.a., with molecular weight of ~31 kDa.

Mouse

Cathepsin K Protein, a thiol protease, is integral to osteoclastic bone resorption and exhibits potent endoprotease activity against fibrinogen under acidic conditions. Additionally, it may play a significant role in extracellular matrix degradation (By similarity). Notably, Cathepsin K is involved in the release of thyroid hormone thyroxine (T4) through limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen, as demonstrated by studies. This dual functionality underscores its importance in bone metabolism and extracellular matrix dynamics, as well as its specific involvement in the regulated release of thyroid hormones.

Ctsk; Cathepsin K; EC 3.4.22.38

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.