protein

Cathepsin K Protein, Human (P.pastoris, His)

HY-P72156A

20 μg;50 μg;100 μg

145;280;450 USD

Cathepsin K Protein, Human (P.pastoris, His)

proteins

P. pastoris

20 μg;50 μg;100 μg

145;280;450 USD

Cathepsin K protein is a thiol protease that plays a crucial role in osteoclastic bone resorption and contributes to bone remodeling. Working under acidic conditions, it exhibits potent endoprotease activity, particularly against fibrinogen, suggesting involvement in extracellular matrix degradation. Cathepsin K Protein, Human (P.pastoris, His) is the recombinant human-derived Cathepsin K, expressed by P. pastoris , with N-6*His labeled tag. The total length of Cathepsin K Protein, Human (P.pastoris, His) is 215 a.a.,

Human

Cathepsin K Protein, a thiol protease, assumes a crucial role in osteoclastic bone resorption, contributing to the intricate process of bone remodeling. This enzyme exhibits potent endoprotease activity, particularly against fibrinogen, under acidic conditions, suggesting its involvement in extracellular matrix degradation. Furthermore, Cathepsin K plays a role in the regulated release of thyroid hormone thyroxine (T4) through limited proteolysis of TG/thyroglobulin within the thyroid follicle lumen, highlighting its multifaceted functions in physiological processes.

Cathepsin K; Cathepsin O; Cathepsin O1; Cathepsin O2; Cathepsin X; CATK_HUMAN; CTS02; Ctsk; CTSO; CTSO1; CTSO2; MGC23107; PKND; PYCD

Greater than 90 % as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.