IL-19 Protein, Human | MedChem Express LLC HY-P7212 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

IL-19 Protein, Human

catalog :

HY-P7212

quantity :

10 μg;50 μg

price :

210;620 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7212

Product Name :

IL-19 Protein, Human

Product Type :

proteins

Host Species :

E. coli

Size :

10 μg;50 μg

List Price :

210;620 USD

list of Pubmed id :

377622346

Product Description :

IL-19 Protein, Human is a member of the Interleukin-10 family. The biological functions and clinical implications of Interleukin-19 is still undefined.

SpeciesSummary :

Human

Background :

IL-19 shares 21% amino acid identity with IL-10. The exon/intron structure of IL-19 is similar to that of the human IL-10 gene, comprising five exons and four introns within the coding region of the IL-19 cDNA. IL-19 does not bind or signal through the canonical IL-10 receptor complex [1] . IL-19 functions through a receptor complex composed of IL-20Ra and IL20Rb that is also utilized by IL-20 and IL-24. IL19 has been shown to enhance the production of Th2 cytokines in Tcells and to be elevated in asthma patients. Furthermore, it induces IL-6, IL-8 and IL-10 expression in monocytes. Additionally, it has been implicated in a range of diseases and disorders, including aging, Type-I diabetes, endotoxic shock, periodontal disease, vascular disease and rheumatoid arthritis [2] .

ALTnames :

rHuIL-19; Melanoma differentiation association like protein; ZMDA1

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS, pH 7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage