protein

BCL2 Protein, Mouse (His)

HY-P72101

5 μg;10 μg;50 μg

75;125;350 USD

BCL2 Protein, Mouse (His)

proteins

E. coli

5 μg;10 μg;50 μg

75;125;350 USD

BCL2 protein crucially regulates cell death by controlling mitochondrial membrane permeability. It interacts with caspases in a feedback loop, inhibiting their activity. BCL2 prevents cytochrome c release from mitochondria and binds to apoptosis-activating factor (APAF-1). BCL2 Protein, Mouse (His) is the recombinant mouse-derived BCL2 protein, expressed by E. coli , with N-6*His labeled tag.

Mouse

BCL2 is a protein that plays a crucial role in regulating cell death, specifically by controlling the permeability of the mitochondrial membrane. It is involved in a feedback loop system with caspases, which are enzymes responsible for initiating cell death. BCL2 inhibits caspase activity by either preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).

Bcl2; Bcl-2; Apoptosis regulator Bcl-2

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.