protein

ASPN Protein, Human (His-SUMO)

HY-P72093

5 μg;10 μg;50 μg;100 μg

80;120;300;510 USD

ASPN Protein, Human (His-SUMO)

Protein

E. coli

5 μg;10 μg;50 μg;100 μg

80;120;300;510 USD

ASPN protein acts as a negative regulator in periodontal ligament (PDL) differentiation and mineralization, preventing ossification and maintaining homeostasis of the tooth support system. It inhibits BMP2-induced cell differentiation by blocking the binding of BMP2 to BMPR1B, thereby preventing BMP-dependent activation of SMAD proteins. ASPN Protein, Human (His-SUMO) is the recombinant human-derived ASPN protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.