protein

Transthyretin/TTR Protein, Human (HEK293, Fc-Myc)

HY-P72026

2 μg;10 μg;50 μg;100 μg

70;196;549;933 USD

Transthyretin/TTR Protein, Human (HEK293, Fc-Myc)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

70;196;549;933 USD

The transthyretin/TTR protein is a thyroid hormone binder that may be critical for transporting thyroxine from the bloodstream to the brain. Its structure is a homotetramer, forming a dimer of dimers, and its central channel is suggested to play a role in thyroxine binding and transport. Transthyretin/TTR Protein, Human (HEK293, Fc-Myc) is the recombinant human-derived Transthyretin/TTR protein, expressed by HEK293 , with C-hFc, C-Myc labeled tag. The total length of Transthyretin/TTR Protein, Human (HEK293, Fc-Myc) is 127 a.a., with molecular weight of ~47 kDa.

Human

Transthyretin/TTR Protein serves as a thyroid hormone-binding protein, likely playing a crucial role in transporting thyroxine from the bloodstream to the brain. Forming a homotetramer, it is structured as a dimer of dimers, with subunits assembling around a central channel capable of accommodating two ligand molecules. This suggests a functional significance in the binding and transport of thyroxine. Additionally, Transthyretin/TTR Protein interacts with RBP4, highlighting potential cooperative actions in the regulation of thyroid hormone dynamics. The homotetrameric configuration and ligand-binding properties underscore the importance of Transthyretin/TTR in facilitating the transport and distribution of thyroid hormones, emphasizing its role in maintaining endocrine balance.

ATTR Prealbumin; TBPA; PALB;

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm solution of PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US;may vary elsewhere.