protein

NRG1-beta 1 Protein, Human (65a.a, His)

HY-P72007

2 μg;10 μg;50 μg;100 μg

35;63;176;300 USD

NRG1-beta 1 Protein, Human (65a.a, His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

35;63;176;300 USD

HRG1-β1 belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes, induces Fn14 expression in MCF7 cells. NRG1-beta 1 Protein, Human (65a.a, His) is the recombinant human-derived NRG1-beta 1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of NRG1-beta 1 Protein, Human (65a.a, His) is 65 a.a., with molecular weight of ~ 7.5 kDa.

Human

HRG1-β1 activates HER2/HER3 signaling and up-regulate Fn14 gene expression in parental MCF7 cells. HRG1-β1-mediated Fn14 up-regulation in MCF7/HER2-18 cells is required for maximal MMP-9 production.

Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; EGF; NRG1; GGF; HGL; HRGA; NDF; SMDF; Heregulin β-1; Heregulin; HRG

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from sterile 50 mM Tris-HCL, 300 mM NaCL, pH 8.0.

Room temperature in continental US; may vary elsewhere.