protein

HCC-4/CCL16 Protein, Human

HY-P7197

2 μg;10 μg;50 μg;100 μg

35;95;260;440 USD

HCC-4/CCL16 Protein, Human

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

35;95;260;440 USD

377622333

HCC-4/CCL16 Protein, Human is a CC chemokine that specifically attracts lymphocytes, dendritic cells and monocytes, increases their adhesion and has myelosuppressive activity. HCC-4/CCL16 Protein, Human interacts with CCR1, CCR2, CCR5 and CCR8 to mediate inflammatory and cancer responses. HCC-4/CCL16 Protein, Human is a recombinant human HCC-4/CCL16 (Q24-Q120) expressed by E. coli [1] .

Human

CCL16, also known as CC chemokine 4, liver expressed chemokine (LEC) and monotactin-1 (MTN-1), is a small cytokine belonging to the CC chemokine family, a cluster of chemokines located on human chromosome 17. CCL16 is also a ligand for the histamine H4 receptor. CCL16 can chemotacticize monocytes and lymphocytes but not neutrophils. Recent studies have shown that CCL16 increases tumor rejection, antigen presentation by macrophages, and angiogenic activity of vascular endothelial cells. On the other hand, CCL16 may also enhance the anticancer effects of cytotoxic T cells and dendritic cell (DC) lymphocytes [1] [2] .

rHuHCC-4/CCL16; C-C motif chemokine 16; SCYA16

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.