IL-36RN Protein, Human | MedChem Express LLC HY-P71965 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

IL-36RN Protein, Human

catalog :

HY-P71965

quantity :

10 μg;50 μg

price :

130;360 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P71965

Product Name :

IL-36RN Protein, Human

Product Type :

proteins

Host Species :

E. coli

Size :

10 μg;50 μg

List Price :

130;360 USD

Product Description :

IL-36RN Protein, Human, a member of the interleukin 1 cytokine family, is a IL-36 receptor antagonist.

SpeciesSummary :

Human

Background :

IL-1F5 (IL-36RN) acts as a receptor antagonist of IL-1RL2 (IL-1Rrp2). It inhibits the multiple stimulatory effects induced by the agonists IL-1F6 (IL-36a), IL-1F8 (IL36b) and IL-1F9 (IL-36c) by preventing them from binding to this receptor. As with IL-1RN, IL-36RN fails to recruit IL-1RAcP on the cell surface. IL-36RN also downregulates inflammation through an interaction with the orphan receptor SIGIRR. Humans possessing a homozygous missense mutation in IL-36RN express low levels of an aberrant protein which has a lower affinity for IL-1RL2 than the wild-type [1] .

ALTnames :

IL-36RA; IL-36Ra; Interleukin-36 Receptor Antagonist Protein; IL-1RP3; Interleukin-1; Interleukin-1 Family Member 5; IL-1F5; Interleukin-1-Like Protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1RP3

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage :

Room temperature in continental US;may vary elsewhere.

more info or order :

MedChem Express LLC product webpage