protein

Neuritin Protein, Human (N-His)

HY-P71908A

5 μg;10 μg;50 μg;100 μg

38;65;180;305 USD

Neuritin Protein, Human (N-His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

38;65;180;305 USD

Neutritin is a key factor in neural development, significantly enhancing neurite growth and branching in hippocampal and cortical cells. In the AMPA receptor (AMPAR) complex, neuronal proteins help form the outer core and regulate the function and properties of these receptors. Neuritin Protein, Human (N-His) is the recombinant human-derived Neuritin protein, expressed by E. coli , with N-6*His labeled tag. The total length of Neuritin Protein, Human (N-His) is 88 a.a., with molecular weight of ~11 kDa.

Human

Neuritin, a key player in neural development, significantly enhances neurite outgrowth and branching in primary hippocampal and cortical cells. Within the AMPA receptor (AMPAR) complex, Neuritin contributes to the outer core, which is part of the intricate architecture that modulates the function and properties of these receptors. The AMPAR complex, consisting of an inner core with pore-forming GluA/GRIA proteins and major auxiliary subunits, involves specific interactions with Neuritin and other components like PRRT1, PRRT2, CKAMP44/SHISA9, FRRS1L, and NRN1 in the outer core. This outer core is crucial for fine-tuning the gating, pharmacology, biogenesis, and protein processing of AMPARs. Neuritin's involvement in the complex network of protein-protein interactions highlights its role as a regulatory element in shaping the functional properties of AMPARs and underscores its significance in neuronal connectivity.

Neuritin 1; Neuritin; NRN; Nrn1; NRN1_HUMAN; OTTHUMP00000015989; RP3 380B8.2 protein

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.