protein

CTACK/CCL27 Protein, Mouse

HY-P71894

2 μg;10 μg;50 μg;100 μg

48;125;350;560 USD

CTACK/CCL27 Protein, Mouse

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

48;125;350;560 USD

CTACK/CCL27 protein attracts skin-associated memory T-lymphocytes, mediating lymphocyte homing to the skin. It may also participate in embryonic cell migration. Nuclear forms of CCL27 induce cytoskeletal relaxation. The protein binds to CCR10, exists in monomeric, dimeric, and tetrameric forms, and heparin promotes oligomerization. Additionally, CCL27 interacts with TNFAIP6 through its Link domain. CTACK/CCL27 Protein, Mouse is the recombinant mouse-derived CTACK/CCL27 protein, expressed by E. coli , with tag free.

Mouse

CCL27 protein acts as a chemotactic factor specifically attracting skin-associated memory T-lymphocytes, potentially playing a crucial role in mediating the homing of lymphocytes to cutaneous sites. This chemokine may also participate in cell migration during embryogenesis. Notably, nuclear forms of CCL27 may contribute to cellular migration by inducing cytoskeletal relaxation. The protein binds to the CCR10 receptor and exists in monomeric, dimeric, and tetrameric forms, with heparin avidly promoting oligomerization. Furthermore, CCL27 interacts with TNFAIP6, specifically via its Link domain.

Ccl27; Ilc; Scya27C-C motif chemokine 27; CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; ALP; mILC; Skinkine; Small-inducible cytokine A27

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm solution of PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.