protein

IL-1RN Protein, Horse (His)

HY-P71876A

2 μg;10 μg;50 μg;100 μg

44;122;341;580 USD

IL-1RN Protein, Horse (His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

44;122;341;580 USD

IL-1RN protein, an anti-inflammatory antagonist, safeguards against immune dysregulation and systemic inflammation triggered by IL1. It acts on proinflammatory cytokines, including IL1B and IL1A, countering the effects of IL1. Particularly responsive to innate stimulatory agents like pathogens, IL-1RN helps mitigate the inflammatory response, ensuring immune homeostasis. IL-1RN Protein, Horse (His) is the recombinant equine-derived IL-1RN protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-1RN Protein, Horse (His) is 152 a.a., with molecular weight of ~18 kDa.

Equine

IL-1RN protein is an anti-inflammatory antagonist that acts on the interleukin-1 family of proinflammatory cytokines, including interleukin-1beta/IL1B and interleukin-1alpha/IL1A. It serves as a protective agent against immune dysregulation and uncontrolled systemic inflammation induced by IL1, particularly in response to various innate stimulatory agents like pathogens. IL-1RN helps mitigate the inflammatory response and maintain immune homeostasis by counteracting the effects of IL1.

IL1RN; IL1RAInterleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; IL1 inhibitor

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.