product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
IL-4 Protein, Rhesus macaque
catalog :
HY-P71859
quantity :
5 μg
price :
350 USD
product information
Catalog Number :
HY-P71859
Product Name :
IL-4 Protein, Rhesus macaque
Product Type :
proteins
Host Species :
E. coli
Size :
5 μg
List Price :
350 USD
Product Description :
IL-4 protein actively engages in B-cell activation, serving as a costimulator for DNA synthesis, inducing class II MHC molecule expression, and enhancing IgE and IgG1 secretion. It regulates CD23 expression on lymphocytes and monocytes, positively influences IL31RA expression in macrophages, and induces autophagy in dendritic cells through mTORC1 signaling interference and RUFY4 induction. IL-4 Protein, Rhesus macaque is the recombinant Rhesus Macaque-derived IL-4 protein, expressed by E. coli , with tag free.
SpeciesSummary :
Rhesus Macaque
Background :
IL-4 protein actively participates in various B-cell activation processes and other cell types, acting as a costimulator of DNA synthesis. Moreover, it induces the expression of class II MHC molecules on resting B-cells and enhances the secretion and cell surface expression of IgE and IgG1. IL-4 also plays a regulatory role in the expression of the low affinity Fc receptor for IgE (CD23) on lymphocytes and monocytes. Additionally, it positively regulates IL31RA expression in macrophages and stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and inducing RUFY4.
ALTnames :
IL4Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1
Purity :
Greater than 95% as determined by reducing SDS-PAGE
Buffer :
Lyophilized from a 0.2 μm solution of 2 xPBS, 5 % Trehalose, pH 7.4 or PBS, pH 7.4, 8% trehalose.
Storage :
Room temperature in continental US; may vary elsewhere.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA