protein

PTK7 Protein, Human (P.pastoris, His)

HY-P71821

5 μg;10 μg;50 μg

148;252;706 USD

PTK7 Protein, Human (P.pastoris, His)

proteins

P. pastoris

5 μg;10 μg;50 μg

148;252;706 USD

The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Human (P.pastoris, His) is the recombinant human-derived PTK7 protein, expressed by P. pastoris , with N-6*His labeled tag.

Human

The PTK7 protein, an inactive tyrosine kinase, plays a significant role in the Wnt signaling pathway, being a component of both the non-canonical (Wnt/planar cell polarity signaling) and canonical Wnt signaling pathways. Its involvement spans diverse cellular processes, including cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 also contributes to critical developmental events, such as embryogenesis, epithelial tissue organization, and angiogenesis. Notably, it interacts with CTNNB1, underlining its participation in Wnt pathway regulation and its impact on cellular functions with broader implications in both normal and pathological contexts.

CCK 4; CCK-4; Colon carcinoma kinase 4; Inactive tyrosine-protein kinase 7; Serum response factor; Srf; Tyrosine-protein kinase-like 7

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.