protein

PTPRZ1 Protein, Human (P.pastoris, His)

HY-P71777

20 μg;50 μg;100 μg

210;400;640 USD

PTPRZ1 Protein, Human (P.pastoris, His)

proteins

P. pastoris

20 μg;50 μg;100 μg

210;400;640 USD

The PTPRZ1 protein is an important tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. It plays a crucial role in guiding the normal differentiation of precursor cells into mature oligodendrocytes and may act as an anti-apoptotic factor. PTPRZ1 Protein, Human (P.pastoris, His) is the recombinant human-derived PTPRZ1 protein, expressed by P. pastoris , with N-His labeled tag.

Human

PTPRZ1 protein, a pivotal protein tyrosine phosphatase, serves as a negative regulator of oligodendrocyte precursor proliferation within the embryonic spinal cord. Its essential role extends to the normal differentiation of precursor cells, guiding their transformation into mature, fully myelinating oligodendrocytes. Additionally, PTPRZ1 may act as a protective factor against apoptosis in oligodendrocytes. Beyond its involvement in oligodendrocyte function, PTPRZ1 is implicated in the establishment of contextual memory, potentially through the dephosphorylation of proteins within crucial signaling cascades. This multifaceted role underscores the significance of PTPRZ1 in the intricate processes of oligodendrocyte development and neural signaling, shedding light on its potential contributions to both cellular differentiation and memory formation.

3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; Phosphacan; PTPRZ

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HCl, 0.5 M NaCl, 6%Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.