protein

Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His)

HY-P71748

20 μg;50 μg

215;406 USD

Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His)

proteins

P. pastoris

20 μg;50 μg

215;406 USD

Plasma kallikrein/KLKB1 enzymatically cleaves Lys-Arg and Arg-Ser bonds, triggering factor XII activation upon binding to a negatively charged surface.It liberates bradykinin from HMW kininogen and is implicated in the renin-angiotensin system, potentially converting prorenin into renin.This highlights the protein's multifaceted role in various physiological processes.Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Plasma kallikrein/KLKB1 protein, expressed by P.pastoris , with N-6*His labeled tag.

Rat

The Plasma kallikrein/KLKB1 protein exhibits enzymatic prowess, specifically cleaving Lys-Arg and Arg-Ser bonds. Upon binding to a negatively charged surface, it triggers a reciprocal activation of factor XII. Additionally, the protein facilitates the liberation of bradykinin from HMW kininogen. Notably, it is implicated in the renin-angiotensin system, potentially contributing to the conversion of prorenin into renin. This multifaceted functionality highlights the protein's involvement in diverse physiological processes.

Klkb1; Klk3; PkPlasma kallikrein; EC 3.4.21.34; Fletcher factor; Kininogenin

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.