protein

Glucose-6-phosphate isomerase Protein, Mouse (P.pastoris, His)

HY-P71738

5 μg;10 μg;50 μg

100;171;480 USD

Glucose-6-phosphate isomerase Protein, Mouse (P.pastoris, His)

proteins

P. pastoris

5 μg;10 μg;50 μg

100;171;480 USD

Glucose-6-phosphate isomerase protein exists in the cytoplasm and has dual functions. It converts glucose-6-phosphate into fructose-6-phosphate, playing a vital role in glycolysis and gluconeogenesis. Glucose-6-phosphate isomerase Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Glucose-6-phosphate isomerase protein, expressed by P. pastoris , with N-6*His labeled tag.

Mouse

Glucose-6-phosphate isomerase protein, localized in the cytoplasm, serves a dual function: it catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, playing a pivotal role in both glycolysis and the reverse reaction during gluconeogenesis. Beyond its enzymatic involvement in metabolic pathways, this protein exhibits additional roles as a secreted cytokine. Functioning as an angiogenic factor (AMF), it stimulates endothelial cell motility, suggesting its participation in angiogenesis. Furthermore, glucose-6-phosphate isomerase acts as a neurotrophic factor known as neuroleukin, specifically influencing spinal and sensory neurons. Notably, it is secreted by lectin-stimulated T-cells, where it induces immunoglobulin secretion. This multifaceted protein showcases its versatility, contributing to both fundamental metabolic processes and exhibiting extracellular functions with implications in angiogenesis, neurotrophic support, and immune responses.

Gpi; Gpi1Glucose-6-phosphate isomerase; GPI; AMF; Neuroleukin; NLK; PHI

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.