protein

ERG Protein, Human (P.pastoris, His)

HY-P71733

5 μg;10 μg;50 μg

75;125;350 USD

ERG Protein, Human (P.pastoris, His)

proteins

P. pastoris

5 μg;10 μg;50 μg

75;125;350 USD

ERG Protein, a transcriptional regulator, recruits SETDB1 histone methyltransferase to modify local chromatin. It interacts with SETDB1 and is identified in an IGF2BP1-dependent mRNP granule complex with untranslated mRNAs. ERG Protein, Human (P.pastoris, His) is the recombinant human-derived ERG protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of ERG Protein, Human (P.pastoris, His) is 486 a.a., with molecular weight of ~57 kDa.

Human

ERG, a transcriptional regulator, is implicated in the modulation of gene expression by potentially facilitating transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. Moreover, ERG has been identified as part of an IGF2BP1-dependent mRNP granule complex that contains untranslated mRNAs, suggesting its involvement in post-transcriptional processes. The interaction with SETDB1 underscores its role in the dynamic interplay of molecular components within cellular pathways, contributing to the intricate regulation of gene expression and chromatin organization.

ERG3; included; ets related; ETS-related gene; KCNH2; Oncogene TMPRSS2/ERG fusion

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0

Room temperature in continental US; may vary elsewhere.