protein

Serum Albumin/ALB Protein, Cynomolgus (P.pastoris, His)

HY-P71711

5 μg;10 μg;50 μg

164;262;800 USD

Serum Albumin/ALB Protein, Cynomolgus (P.pastoris, His)

proteins

P. pastoris

5 μg;10 μg;50 μg

164;262;800 USD

Serum albumin (ALB) protein binds a variety of substances, including water, calcium, sodium, potassium, fatty acids, hormones, bilirubin, and drugs. It regulates blood osmolality and transports zinc, calcium and magnesium. Serum Albumin/ALB Protein, Cynomolgus (P.pastoris, His) is the recombinant cynomolgus-derived Serum Albumin/ALB protein, expressed by P. pastoris , with N-His labeled tag. The total length of Serum Albumin/ALB Protein, Cynomolgus (P.pastoris, His) is 584 a.a., with molecular weight of ~68.0 kDa.

Cynomolgus

Serum Albumin (ALB) protein serves various roles, including binding water, calcium, sodium, potassium, fatty acids, hormones, bilirubin, and drugs. Its primary function involves regulating the colloidal osmotic pressure of blood. ALB acts as a major transporter of zinc in plasma, binding approximately 80% of all plasma zinc. It also serves as a significant transporter for calcium and magnesium, binding approximately 45% of circulating calcium and magnesium in plasma. ALB potentially possesses multiple calcium-binding sites and may additionally bind calcium in a non-specific manner. The presence of a shared binding site between zinc and calcium at residue Asp-273 suggests a potential interaction and communication between zinc and calcium transport in the blood, with zinc exhibiting higher affinity followed by calcium and magnesium. ALB also interacts with bacterial siderophore enterobactin, impeding enterobactin-mediated iron uptake by E.coli from ferric transferrin and thereby limiting the utilization of iron and the growth of enteric bacteria like E.coli. However, it does not hinder iron uptake by the bacterial siderophore aerobactin. ALB interacts with FCGRT to regulate its homeostasis and also interacts with TASOR. In plasma, ALB forms a covalently-linked complex with chromophore-bound alpha-1-microglobulin, yet this interaction does not hinder the binding of fatty acids to ALB.

ALB; Qlv-U347A-C12; Qlv-U377A-G8Serum albumin

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.