protein

Transcription termination factor Rho Protein, E.coli (His)

HY-P71705

5 μg;10 μg;50 μg

143;243;680 USD

Transcription termination factor Rho Protein, E.coli (His)

proteins

E. coli

5 μg;10 μg;50 μg

143;243;680 USD

The transcription terminator Rho protein plays a key role in promoting transcription termination through a mechanism that binds to nascent RNA, activates Rho's RNA-dependent ATPase activity, and subsequently releases mRNA from the DNA template. As an RNA-dependent NTPase, Rho utilizes all four ribonucleoside triphosphates as substrates, highlighting its versatility in nucleotide interactions during termination. Transcription termination factor Rho Protein, E.coli (His) is the recombinant E. coli-derived Transcription termination factor Rho protein, expressed by E. coli , with N-6*His labeled tag. The total length of Transcription termination factor Rho Protein, E.coli (His) is 419 a.a., with molecular weight of ~51.0 kDa.

E.coli

The Transcription termination factor Rho protein, crucial for the regulation of gene expression, facilitates transcription termination through a well-defined mechanism. This process involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and subsequent release of the mRNA from the DNA template. As an RNA-dependent NTPase, Rho utilizes all four ribonucleoside triphosphates as substrates, highlighting its versatility in nucleotide interactions during the termination process. Notably, the ATPase activity of Rho is susceptible to inhibition by bicyclomycin and dihydrobicyclomycin, providing potential avenues for pharmacological modulation of Rho-mediated transcription termination.

rho; nitA; psuA; rnsC; sbaA; tsu; b3783; JW3756; Transcription termination factor Rho; ATP-dependent helicase Rho

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μ m sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 6%Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.