protein

HGF Protein, Rat (GST)

HY-P71688

5 μg;10 μg;50 μg

85;145;400 USD

HGF Protein, Rat (GST)

proteins

E. coli

5 μg;10 μg;50 μg

85;145;400 USD

HGF Protein, a potent mitogen, stimulates mature hepatocyte cell growth, acting as a hepatotrophic factor for various tissues.It activates MAPK signaling through TMPRSS13 cleavage and activates MET receptor tyrosine kinase by promoting its dimerization.Structurally, HGF comprises alpha and beta chains connected by a disulfide bond.Interaction with SRPX2 enhances its mitogenic activity.HGF Protein, Rat (GST) is the recombinant rat-derived HGF protein, expressed by E.coli , with N-GST labeled tag.

Rat

HGF protein is a potent mitogen that stimulates the growth of mature parenchymal hepatocyte cells. It functions as a hepatotrophic factor and acts as a growth factor for various tissues and cell types. HGF serves as an activating ligand for the receptor tyrosine kinase MET, promoting its dimerization. Furthermore, it activates MAPK signaling through TMPRSS13 cleavage and activation. Structurally, HGF is composed of an alpha chain and a beta chain connected by a disulfide bond. It also interacts with SRPX2, which enhances the mitogenic activity of HGF.

Hgf; Hepatocyte growth factor; Hepatopoietin-A

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.