protein

C1QTNF3/CTRP3 Protein, Human (His)

HY-P71648

5 μg;10 μg;50 μg

82;140;390 USD

C1QTNF3/CTRP3 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg

82;140;390 USD

C1QTNF3/CTRP3 Protein is a secreted protein of the C1q/ TNF-associated protein (CTRPs) family. C1QTNF3/CTRP3 Protein by participating in the TGF-尾1/Smad , Sirtuin 1/NF-魏B , AMPK and Signaling pathways such as LAMP1/JIP2/JNK have extensive effects on tumor, inflammation, metabolism, and insulin sensitization. C1QTNF3/CTRP3 Protein, Human (His) is the recombinant human-derived C1QTNF3/CTRP3 protein, expressed by E. coli , with N-His labeled tag.

Human

C1q/ TNF-associated proteins (CTRPs) are a family of secreted proteins with a specific structure. CTRPs have a wide range of effects on survival signaling, inflammation, metabolism and insulin sensitization. Complement C1q tumor necrosis factor-related protein 3 inhibits proliferation, migration, and ECM accumulation in keloid fibroblasts by regulating TGF-β1/Smad signaling pathway. Play an anti-fibrotic role. C1QTNF3 is involved in the pathogenesis and insulin resistance of polycystic ovary syndrome (PCOS). C1qtnf3 reduces intestinal inflammation through the Sirtuin 1/NF-κB signaling pathway. C1QTNF3 affects lipid metabolism and necrotic inflammation of renal tubular cells through AMPK signaling pathway. C1QTNF3 alleviates myocardial ischemia/reperfusion injury in mice by activating the LAMP1/JIP2/JNK pathway [1] [2] [3] [4] [5] .

C1ATNF3; C1q and tumor necrosis factor related protein 3 Complement C1q tumor necrosis factor related protein 3 ; Complement C1q tumor necrosis factor-related protein 3; Corcs; CORS 26; Cors; CORS26; CTRP3; FLJ37576

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.