protein

cGAS Protein, Human (His-SUMO)

HY-P71597

5 μg;10 μg;50 μg;100 μg

59;100;280;475 USD

cGAS Protein, Human (His-SUMO)

Protein

E. coli

5 μg;10 μg;50 μg;100 μg

59;100;280;475 USD

The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2',3'-cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA). As a DNA sensor, cGAS detects exogenous and endogenous DNA, triggering STING1 activation and type I interferon production. cGAS Protein, Human (His-SUMO) is the recombinant human-derived cGAS protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.