protein

CDTB Protein, E.coli (Myc, His-SUMO)

HY-P71555

10 μg;20 μg;50 μg;100 μg

175;280;520;840 USD

CDTB Protein, E.coli (Myc, His-SUMO)

Protein

E.coli

10 μg;20 μg;50 μg;100 μg

175;280;520;840 USD

CDTB Protein, integral to the tripartite complex for Cytolethal Distending Toxin (CDT) activity, features DNA-nicking endonuclease action, likely causing DNA damage. This damage prompts G2/M cell cycle arrest, chromatin fragmentation, cell distention, and nucleus enlargement. Collaborating with CdtA and CdtC, CDTB forms a crucial unit for CDT's cytotoxic effects, showcasing its multifaceted role in cellular responses to CDT intoxication. CDTB Protein, E.coli (Myc, His-SUMO) is the recombinant E. coli-derived CDTB protein, expressed by E. coli , with N-His, C-Myc, N-SUMO labeled tag.