protein

JMJD1C Protein, Human (His-SUMO-Myc)

HY-P71548

5 μg;10 μg;20 μg;50 μg;100 μg

88;150;232;420;650 USD

JMJD1C Protein, Human (His-SUMO-Myc)

proteins

E. coli

5 μg;10 μg;20 μg;50 μg;100 μg

88;150;232;420;650 USD

The JMJD1C protein is a possible histone demethylase that centrally affects the histone code by targeting “Lys-9” of histone H3. Its enzymatic activity produces formaldehyde and succinic acid. JMJD1C Protein, Human (His-SUMO-Myc) is the recombinant human-derived JMJD1C protein, expressed by E. coli , with C-Myc, N-SUMO, N-10*His labeled tag.

Human

The JMJD1C protein is identified as a probable histone demethylase with a specific role in demethylating 'Lys-9' of histone H3, thereby exerting a central influence on the histone code. This demethylase activity results in the generation of formaldehyde and succinate. Beyond its enzymatic function, JMJD1C is implicated in potential involvement in hormone-dependent transcriptional activation, suggested by its participation in the recruitment to androgen-receptor target genes. This multifaceted role underscores JMJD1C's significance in epigenetic regulation and its potential contribution to the dynamic interplay of histone modifications in the context of gene expression.

Jmjd1c; Jumonji domain containing 1C ; Jumonji domain-containing protein 1C; Probable JmjC domain-containing histone demethylation protein 2C; Thryoid receptor interacting protein; Thyroid receptor-interacting protein 8; TR-interacting protein 8; TRIP-8; TRIP8

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.