protein

ST3GAL3 Protein, Human (His-SUMO)

HY-P71529

20 μg;50 μg

105;235 USD

ST3GAL3 Protein, Human (His-SUMO)

proteins

E. coli

20 μg;50 μg

105;235 USD

ST3GAL3 protein plays a central role in cellular processes by catalyzing the formation of NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-α-2,3-Gal-beta-1,3-GalNAc- sequences are present in the terminal carbohydrate groups of glycoproteins and glycolipids. ST3GAL3 Protein, Human (His-SUMO) is the recombinant human-derived ST3GAL3 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of ST3GAL3 Protein, Human (His-SUMO) is 347 a.a., with molecular weight of ~54.9 kDa.

Human

ST3GAL3, or sialyltransferase 3, is an enzyme that catalyzes the formation of terminal carbohydrate sequences on glycoproteins and glycolipids. Specifically, it is responsible for adding sialic acid to the Gal-beta-1,3-GlcNAc, Gal-beta-1,3-GlcNAc, and Gal-beta-1,3-GalNAc structures, resulting in the formation of NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc, and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequences. These sialylation events play a crucial role in modulating the structure and function of glycoproteins and glycolipids, impacting various cellular processes. ST3GAL3 exhibits varying degrees of activity towards different substrates, with the highest activity observed towards Gal-beta-1,3-GlcNAc and the lowest towards Gal-beta-1,3-GalNAc. It has to succinctly outline ST3GAL3's role in catalyzing the addition of sialic acid to specific carbohydrate structures, highlighting its contribution to the diversity of terminal glycan sequences in biological molecules.

3 sialyltransferase; 3(4) GlcNAc alpha-2; 3-sialyltransferase 3; 3-sialyltransferase; 3-ST 3; 4-galactoside alpha-2; 4GlcNAc alpha 2 3 sialyltransferase; Alpha 2 3 sialyltransferase II; Alpha 2 3 sialyltransferase III; Alpha 2 3 ST 3; Alpha 2; Beta galactoside alpha 3 sialyltransferase 3; Beta-galactoside alpha-2; CMP N acetylneuraminate beta 1 4 galactoside alpha 2 3 sialyltransferase; CMP-N-acetylneuraminate-beta-1; EC 2.4.99.6; Gal beta 1 3; Gal beta 1 3(4) GlcNAc alpha 2 3 sialyltransferase; Gal beta 1 3(4)GlcNAc alpha 2 3 sialyltransferase; Gal beta-1; N acetyllactosaminide alpha 2 3 sialyltransferase; N-acetyllactosaminide alpha-2; OTTHUMP00000008820; OTTHUMP00000008821; OTTHUMP00000008822; OTTHUMP00000008823; Sialyltransferase 6 (N acetyllacosaminide alpha 2 3 sialyltransferase); Sialyltransferase 6; SIAT6; SIAT6_HUMAN; ST3 beta galactoside alpha 2 3 sialyltransferase 3; ST3 beta galactoside alpha 2,3 sialyltransferase 3; ST3Gal III; St3gal3; ST3GALII; ST3GalIII; ST3N

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.