protein

FGF-15 Protein, Mouse (His-SUMO)

HY-P71526

5 μg;10 μg;50 μg;100 μg

55;90;245;420 USD

FGF-15 Protein, Mouse (His-SUMO)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

55;90;245;420 USD

FGF-15 Protein crucially suppresses bile acid biosynthesis by down-regulating CYP7A1 expression, contributing to intricate bile acid homeostasis control. Interacting with MALRD1 suggests potential involvement in molecular pathways beyond bile acid regulation. The molecular associations and regulatory functions underscore FGF-15's significance in maintaining physiological balance, particularly in bile acid metabolism. FGF-15 Protein, Mouse (His-SUMO) is the recombinant mouse-derived FGF-15 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of FGF-15 Protein, Mouse (His-SUMO) is 193 a.a., with molecular weight of ~38 kDa.

Mouse

The FGF-15 Protein plays a crucial role in the suppression of bile acid biosynthesis by down-regulating CYP7A1 expression. Through its regulatory activity, FGF-15 contributes to the intricate control of bile acid homeostasis. Additionally, the protein interacts with MALRD1, suggesting potential involvement in molecular pathways and processes beyond bile acid regulation. The molecular associations and regulatory functions of FGF-15 highlight its significance in maintaining physiological balance, particularly in the context of bile acid metabolism.

FGF-15; Fgf15; FGF15_MOUSE; FGF19; Fibroblast growth factor 15

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4 or 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0.

Room temperature in continental US; may vary elsewhere.