Cardiotrophin-1/CTF1 Protein, Mouse (HEK293) | MedChem Express LLC HY-P7150 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

Cardiotrophin-1/CTF1 Protein, Mouse (HEK293)

catalog :

HY-P7150

quantity :

10 μg;50 μg

price :

150;450 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7150

Product Name :

Cardiotrophin-1/CTF1 Protein, Mouse (HEK293)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

150;450 USD

list of Pubmed id :

377622287

Product Description :

Cardiotrophin-1/CTF1 Protein, Mouse (HEK293, His), a member of IL-6 family of cytokines, is required for cardiac myocyte maturation and plays an important role in the differentiation, development, and survival of neural stem cells.

SpeciesSummary :

Mouse

Background :

Cardiotrophin-1 (CT-1) is required for cardiac myocyte maturation and is capable of promoting cell survival in neonatal rat cardiomyocytes subjected to serum deprivation through an antiapoptotic pathway mediated by MAPK, ERK1/2CT1 [1] . CT-1 exhibits impressive neuroprotective effects and delay the procession of motor neuron degenerative disorders by prolonging the median neuronal survival time, improving motor function and promoting regeneration in neonatal rat motor neurons in mouse models of amyotrophic lateral sclerosis, progressive motor neuropathy and spinal muscular atrophy and in adult rats with spinal cord injuries [2] .

ALTnames :

rMuCT-1; CTF1

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage