protein

HADHB Protein, Human (GST)

HY-P71471

10 μg;50 μg

125;350 USD

HADHB Protein, Human (GST)

proteins

E. coli

10 μg;50 μg

125;350 USD

HADHB protein is an important component of mitochondrial trifunctional enzymes and directs three decisive reactions in the mitochondrial β-oxidation pathway. This pathway is critical for generating energy across tissues, breaking down long-chain fatty acids into acetyl-CoA. HADHB Protein, Human (GST) is the recombinant human-derived HADHB protein, expressed by E. coli , with N-GST labeled tag.

Human

HADHB protein serves as an integral component of the mitochondrial trifunctional enzyme, orchestrating the final three reactions within the mitochondrial beta-oxidation pathway. This crucial pathway is paramount for energy production in various tissues, breaking down fatty acids into acetyl-CoA through a series of four consecutive reactions. Specifically tailored for long-chain fatty acids, the trifunctional enzyme operates as a heterotetrameric complex composed of two distinct subunits. HADHA, carrying 2,3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, partners with HADHB, the focus here, which houses the 3-ketoacyl-CoA thiolase activity. This intricate collaboration underscores HADHB's pivotal role in driving the final steps of mitochondrial beta-oxidation, contributing to energy homeostasis in cellular metabolism.

3-ketoacyl-CoA thiolase; Acetyl CoA acyltransferase; Acetyl-CoA acyltransferase; Beta ketothiolase; Beta-ketothiolase; ECHB; ECHB_HUMAN; HADH; Hadhb; beta subunit; Hydroxyacyl Coenzyme A (CoA) dehydrogenase beta subunit; MGC87480; MSTP 029; MSTP029; MTPB; TP beta; TP-beta; TPbeta; Trifunctional enzyme subunit beta; Trifunct

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against solution in 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.