protein

BD-4 Protein, Human

HY-P7140

5 μg;10 μg;50 μg;100 μg

47;80;250;425 USD

BD-4 Protein, Human

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

47;80;250;425 USD

377622277

BD-4 Protein, Human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity.

Human

Human Beta Defensin-4 (hBD-4) expression is up-regulated by infection with gram-positive and gram-negative bacteria in human respiratory epithelial cells, and in response to phorbol 12-myristate 13-acetate, but not in response to other inflammatory factors that up-regulate the expression of hBD-2 or hBD-3. Synthetic hBD-4 exhibits a selective, salt-sensitive spectrum of antimicrobial activity, and it represents one of the most active antimicrobial peptides against Pseudomonas aeruginosa (minimal inhibitory concentration: 4.1 μg/mL) known to date [1] .

rHuBD-4; DEFB-4; Beta-defensin 104; DEFB4; DEFB104

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, pH 7.4, 130 mM NaCl or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.