protein

TXLNA Protein, Human (His)

HY-P71392

10 μg;50 μg

170;510 USD

TXLNA Protein, Human (His)

proteins

E. coli

10 μg;50 μg

170;510 USD

The TXLNA protein may be involved in intracellular vesicle trafficking, specifically calcium-dependent exocytosis in neuroendocrine cells. Its binding kinetics involve interactions with the C-terminal coiled-coil region of synaptophysin family members such as STX1A, STX3A, and STX4A. TXLNA Protein, Human (His) is the recombinant human-derived TXLNA protein, expressed by E. coli , with N-6*His, C-6*His labeled tag. The total length of TXLNA Protein, Human (His) is 162 a.a., with molecular weight of ~30.0 kDa.

Human

TXLNA Protein emerges as a potential participant in intracellular vesicle traffic and may play a role in calcium-dependent exocytosis in neuroendocrine cells. Its interaction dynamics are characterized by binding to the C-terminal coiled coil region of syntaxin family members, including STX1A, STX3A, and STX4A. Notably, this binding occurs when these syntaxins are not complexed with SNAP25, VAMP2, or STXBP1, implying that TXLNA interacts specifically with syntaxins that are not part of the SNARE complex. The specificity of its interactions suggests a nuanced role in intracellular vesicle trafficking, potentially influencing neuroendocrine cell functions. Elucidating the precise mechanisms through which TXLNA modulates vesicle traffic and its involvement in calcium-dependent exocytosis could provide valuable insights into its functional significance in cellular processes related to neurotransmission and secretion.

Alpha-Taxilin; TXLNA; TXLN

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US;may vary elsewhere.