protein

TPSAB1 Protein, Human (HEK293, His)

HY-P71377

10 μg;50 μg

170;510 USD

TPSAB1 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

170;510 USD

Tryptase alpha/beta 1 protein (TPSAB1) belongs to a family of trypsin-like serine proteases, and is enzymatically active and get involved in proteolysis only as heparin-stabilized tetramers, TPSAB1 is also resistant to all known endogenous proteinase inhibitors. Beta tryptase appears to be the main isoenzymes expressed in mast cells; while alpha tryptase is predominate in basophils. TPSAB1 Protein, Human (HEK293, His) is the recombinant human-derived TPSAB1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TPSAB1 Protein, Human (HEK293, His) is 245 a.a., with molecular weight of 32-37 kDa.

Human

Tryptase alpha/beta 1 protein (TPSAB1) belongs to a family of trypsin-like serine proteases, the peptidase family S1. TPSAB1is enzymatically active and get involved in proteolysis only as heparin-stabilized tetramers, and TPSAB1is resistant to all known endogenous proteinase inhibitors. Beta tryptase appears to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptase predominate. TPSAB1 has been implicated as mediators in the pathogenesis of asthma, inflammatory bowel disease, inflammatory arthritis and other allergic and inflammatory disorders [1] [2] [3] [4] .

tryptase alpha/beta 1; Tryptase 1; TPS1; TPS2; TPSAB1; TPSB1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 1 M NaCl, 0.05 mM Heparin, 50 mM sodium acetate, containing 0.01% sodium azide, pH 5.0.

Room temperature in continental US;may vary elsewhere.