protein

TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His)

HY-P71365

10 μg;50 μg

90;270 USD

TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His)

proteins

HEK293

10 μg;50 μg

90;270 USD

The TIM-1/KIM-1/HAVCR protein is a phosphatidylserine receptor that is critical for B cell homeostasis, affecting generation, expansion, and inhibitory functions. As a P-selectin/SELPLG ligand, it facilitates trafficking of activated T cells during inflammation and controls T cell accumulation in the inflamed central nervous system. TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with C-6*His labeled tag.

Mouse

TIM-1/KIM-1/HAVCR Protein is a phosphatidylserine receptor that plays a crucial role in regulating B-cell homeostasis, including their generation, expansion, and suppressor functions. It functions as a P-selectin/SELPLG ligand, facilitating the trafficking of activated T-cells during inflammatory responses. This protein is involved in controlling T-cell accumulation in the inflamed central nervous system (CNS) and the development of autoimmune diseases. It also regulates the expression of several anti-inflammatory cytokines and co-inhibitory ligands, such as IL10. Additionally, TIM-1/KIM-1/HAVCR Protein acts as a regulator of T-cell proliferation and may have a role in kidney injury and repair. It interacts with STAM and SELPLG.

Hepatitis A virus cellular receptor 1 homolog; HAVcr-1; Kidney injury molecule 1; KIM-1; T cell membrane protein 1; TIM-1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US;may vary elsewhere.