product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
SULT1A3 Protein, Human (N-His)
catalog :
HY-P71341A
quantity :
5 μg;10 μg;50 μg;100 μg;500 μg;1 mg
price :
62;100;300;480;1340;1900 USD
product information
Catalog Number :
HY-P71341A
Product Name :
SULT1A3 Protein, Human (N-His)
Product Type :
proteins
Host Species :
E. coli
Size :
5 μg;10 μg;50 μg;100 μg;500 μg;1 mg
List Price :
62;100;300;480;1340;1900 USD
Product Description :
SULT1A3 protein, a sulfotransferase utilizing PAPS, catalyzes the sulfate conjugation of phenolic monoamines, including neurotransmitters (dopamine, norepinephrine, serotonin) and drugs. This activity contributes significantly to inactivation and elimination, emphasizing SULT1A3's crucial role in regulating neurotransmitter and drug levels, maintaining homeostasis, and ensuring proper biological system functioning. SULT1A3 Protein, Human (N-His) is the recombinant human-derived SULT1A3, expressed by E. coli , with N-6*His labeled tag. ,
SpeciesSummary :
Human
Background :
SULT1A3 protein, a sulfotransferase utilizing 3'-phospho-5'-adenylyl sulfate (PAPS) as its sulfonate donor, plays a pivotal role in catalyzing the sulfate conjugation of phenolic monoamines, including neurotransmitters such as dopamine, norepinephrine, and serotonin, as well as phenolic and catechol drugs. This enzymatic activity contributes significantly to the inactivation and elimination of these bioactive molecules, highlighting SULT1A3's crucial role in regulating the levels and activity of neurotransmitters and certain pharmacologically relevant compounds. The substrate specificity of SULT1A3 underscores its importance in modulating physiological responses to neurotransmitters and drugs, emphasizing its significance in maintaining homeostasis and proper functioning of biological systems.
ALTnames :
Sulfotransferase 1A3/1A4; ST1A3/ST1A4; Aryl Sulfotransferase 1A3/1A4; Catecholamine-Sulfating Phenol Sulfotransferase; HAST3; M-PST; Monoamine-Sulfating Phenol Sulfotransferase; Placental Estrogen Sulfotransferase; Sulfotransferase Monoamine-Preferring; Thermolabi
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose, 8% mannitol and 0.02% Tween80.
Storage :
Room temperature in continental US; may vary elsewhere.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA