protein

SNAP-alpha Protein, Human (His)

HY-P71326

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

56;95;265;450;1200;1700 USD

SNAP-alpha Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

56;95;265;450;1200;1700 USD

SNAP-α proteins are critical in vesicle trafficking, mediating dynamic exchange between the endoplasmic reticulum and the Golgi apparatus. It cooperates with GNA12 to localize CDH5 to the plasma membrane. SNAP-alpha Protein, Human (His) is the recombinant human-derived SNAP-alpha protein, expressed by E. coli , with N-6*His labeled tag. The total length of SNAP-alpha Protein, Human (His) is 295 a.a., with molecular weight of 33-35 kDa.

Human

SNAP-alpha Protein stands as an indispensable player in vesicular transport, facilitating the dynamic exchange between the endoplasmic reticulum and the Golgi apparatus. Its collaboration with GNA12 extends its influence, promoting the localization of CDH5 to the plasma membrane. Moreover, SNAP-alpha engages in intricate protein interactions, forming complexes with PRKCABP and participating in the disruption of the interaction between GRIA2 and PRKCABP, consequently driving the internalization of GRIA2. Within a sophisticated SNARE-like assembly, SNAP-alpha takes its place alongside ZW10, USE1L, RINT1, STX18, and NAPA, revealing its integral role in membrane fusion events. This versatile protein further expands its interaction repertoire by engaging with VAMP8, VTI1A, and STX12. The complex interplay of SNAP-alpha in diverse cellular processes underscores its significance as a key orchestrator in the intricate landscape of intracellular transport and membrane dynamics.

Alpha-Soluble NSF Attachment Protein; SNAP-Alpha; N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha; NAPA; SNAPA

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of sterile 20 mM Tris-HCl, 150 mM NaCl, pH 8.0 or 50 mM Tris-HCL, 300 mM NaCl, pH 7.4, 5% trehalose, 5% mannitol and 0.01%Tween 80.

Room temperature in continental US;may vary elsewhere.