protein

SLP-76 Protein, Human (His-T7)

HY-P71320

10 μg;50 μg

170;510 USD

SLP-76 Protein, Human (His-T7)

proteins

E. coli

10 μg;50 μg

170;510 USD

The SLP-76 protein is critical in T cell antigen receptor-mediated signaling and participates in multiple molecular interactions. Its association with SLA coordinates T cell signaling, whereas its interaction with CBLB emphasizes regulatory effects. SLP-76 Protein, Human (His-T7) is the recombinant human-derived SLP-76 protein, expressed by E. coli , with N-T7, C-6*His labeled tag. The total length of SLP-76 Protein, Human (His-T7) is 533 a.a., with molecular weight of ~70.0 kDa.

Human

SLP-76 protein is a key player in T-cell antigen receptor-mediated signaling, intricately participating in various molecular interactions. Notably, it interacts with SLA, contributing to the orchestration of T-cell signaling events. Its association with CBLB emphasizes its involvement in regulatory processes. Additionally, SLP-76 engages in crucial interactions with signaling proteins, such as GRB2 and SHB, highlighting its role in signal transduction cascades. Moreover, SLP-76 forms complexes with PRAM1, contributing to the intricate network of protein interactions within T-cell signaling pathways. The binding between SLP-76 and CD6, particularly with the tyrosine-phosphorylated C-terminus of CD6, further underscores its significance in mediating cellular responses. Furthermore, SLP-76 interacts with FYB1 and the phosphorylated form of FYB2, adding another layer of complexity to its regulatory functions in T-cell signaling.

Lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein; SLP76; LCP2

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 20% Glycerol, pH 8.5.

Shipping with dry ice.