protein

Serpin B12 Protein, Human (HEK293, His)

HY-P71304

10 μg;50 μg

150;450 USD

Serpin B12 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

150;450 USD

Serpin B12 Protein inhibits trypsin and plasmin, excluding thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. It may have a role in cell differentiation, interacting with SLFN12 in a pathway regulating differentiation, and potentially interacting with USP14. Serpin B12 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B12 Protein, Human (HEK293, His) is 425 a.a., with molecular weight of ~55.0 kDa.

Human

Serpin B12 protein acts as an inhibitor of trypsin and plasmin, displaying specificity by not inhibiting thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. This selective inhibitory profile suggests a nuanced regulatory role in protease-mediated processes. Additionally, Serpin B12 may contribute to cell differentiation, as indicated by its interaction with SLFN12 in a pathway associated with the regulation of cell differentiation. The potential interaction with USP14 further suggests the involvement of Serpin B12 in intricate cellular processes, warranting further exploration of its multifaceted functions.

SERPINB12; Serpin B12; Serine Protease Inhibitor-clade B12

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4 or 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.

Room temperature in continental US; may vary elsewhere.