protein

Serpin G1 Protein, Mouse (HEK293, His)

HY-P71297

10 μg;50 μg

170;510 USD

Serpin G1 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg

170;510 USD

Serpin G1 protein, also known as C1 inhibitor, regulates complement activation, coagulation, fibrinolysis, and kinin production. It forms an inactive complex with C1r or C1s protease and controls C1 complex activation. Serpin G1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin G1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin G1 Protein, Mouse (HEK293, His) is 485 a.a., with molecular weight of 92-95 kDa.

Mouse

Serpin G1 Protein, also known as C1-inhibitor, plays a significant role in regulating crucial physiological pathways including complement activation, blood coagulation, fibrinolysis, and the generation of kinins. It forms a proteolytically inactive complex with the C1r or C1s proteases, thus controlling the activation of the C1 complex. Serpin G1 Protein efficiently inhibits FXIIa and may also inhibit chymotrypsin and kallikrein. Additionally, it interacts with MASP1. By exerting its inhibitory effects, Serpin G1 Protein helps maintain the balance of these complex pathways, ensuring proper physiological functions and preventing excessive activation that could lead to pathological conditions.

SERPIN G1; Plasma protease C1 inhibitor; C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; Serping1; C1nh

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.

Room temperature in continental US;may vary elsewhere.