protein

Serpin D1 Protein, Mouse (HEK293, His)

HY-P71293

10 μg;50 μg

153;430 USD

Serpin D1 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg

153;430 USD

Serpin D1 is a thrombin inhibitor that is activated by glycosaminoglycans such as heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II surpasses antithrombin III (AT) as the primary thrombin inhibitor. Serpin D1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin D1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin D1 Protein, Mouse (HEK293, His) is 455 a.a., with molecular weight of 70-90 kDa.

Mouse

The Serpin D1 protein acts as a thrombin inhibitor, activated by glycosaminoglycans like heparin or dermatan sulfate. When dermatan sulfate is present, HC-II supersedes antithrombin III (AT) as the primary thrombin inhibitor. Additionally, Serpin D1 exhibits chymotrypsin inhibition, but this is glycosaminoglycan-independent. Its predominant expression is observed in the liver.

Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; Serpin D1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 150 mM NaCl, 5% Mannitol, 0.06% Tween80, pH 8.0.

Room temperature in continental US; may vary elsewhere.