protein

PSP Protein, Human (His)

HY-P71241

10 μg;50 μg

120;360 USD

PSP Protein, Human (His)

proteins

E. coli

10 μg;50 μg

120;360 USD

PSP protein catalyzes the final irreversible step in carbohydrate biosynthesis of L-serine through dephosphorylation of O-phospho-L-serine. PSP Protein, Human (His) is the recombinant human-derived PSP protein, expressed by E. coli , with C-6*His labeled tag. The total length of PSP Protein, Human (His) is 225 a.a., with molecular weight of 25-30 kDa.

Human

Phosphoserine phosphatase (PSP) is responsible for catalyzing the final irreversible step in the biosynthesis of L-serine from carbohydrates, involving the dephosphorylation of O-phospho-L-serine to L-serine. This enzymatic activity is pivotal for various cellular processes, as L-serine serves as a precursor for protein synthesis, the generation of other amino acids, nucleotide metabolism, and glutathione synthesis. Additionally, L-serine can undergo racemization to form D-serine, which functions as a neuromodulator. PSP's role in regulating the availability of L-serine underscores its significance in diverse metabolic pathways and cellular functions. There is also a potential involvement in the dephosphorylation of O-phospho-D-serine, although this aspect remains to be confirmed.

Phosphoserine Phosphatase; PSP; PSPase; L-3-Phosphoserine Phosphatase; O-Phosphoserine Phosphohydrolase; PSPH

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 4 M Urea, 5 mM EDTA, pH 8.0.

Shipping with dry ice.