protein

PRDX4 Protein, Human (His)

HY-P71232

10 μg;50 μg

170;510 USD

PRDX4 Protein, Human (His)

proteins

E. coli

10 μg;50 μg

170;510 USD

PRDX4, a thiol-specific peroxidase, enzymatically reduces hydrogen peroxide and organic hydroperoxides, crucial for cellular protection. It detoxifies peroxides, acts as a sensor for hydrogen peroxide-mediated signaling, and contributes to NF-kappa-B activation regulation. PRDX4's multifaceted activity underscores its significance in cellular redox homeostasis and potential impact on intracellular signaling. PRDX4 Protein, Human (His) is the recombinant human-derived PRDX4 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PRDX4 Protein, Human (His) is 234 a.a., with molecular weight of 27-30 kDa.

Human

PRDX4, a thiol-specific peroxidase, functions as an enzymatic catalyst in the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Its pivotal role in cellular protection involves detoxifying peroxides and serving as a sensor for hydrogen peroxide-mediated signaling events. Additionally, PRDX4 contributes to the regulation of NF-kappa-B activation in the cytosol by modulating the phosphorylation of I-kappa-B-alpha. This multifaceted activity underscores the significance of PRDX4 in cellular redox homeostasis and its potential impact on intracellular signaling pathways.

Peroxiredoxin-4; Antioxidant Enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin Peroxidase AO372; Thioredoxin-Dependent Peroxide Reductase A0372; PRDX4

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice.