protein

PPC-DC Protein, Human (His)

HY-P71222

5 μg;10 μg;50 μg;100 μg;500 μg

67;115;320;540;1200 USD

PPC-DC Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg

67;115;320;540;1200 USD

PPC-DC proteins are central players in cellular ubiquitination, covalently linking ubiquitin to target proteins. Its critical role extends to the selective degradation of misfolded membrane proteins, an important process in endoplasmic reticulum-associated degradation (ERAD). PPC-DC Protein, Human (His) is the recombinant human-derived PPC-DC protein, expressed by E. coli , with N-6*His labeled tag.

Human

UBE2J2 protein serves as a key player in cellular ubiquitination processes, facilitating the covalent attachment of ubiquitin to target proteins. Its functional significance extends to the selective degradation of misfolded membrane proteins, a crucial aspect of endoplasmic reticulum-associated degradation (ERAD). This involvement underscores UBE2J2's role in maintaining cellular homeostasis by actively participating in the quality control of protein folding within the endoplasmic reticulum. Additionally, in collaboration with the GATOR2 complex, UBE2J2 catalyzes the 'Lys-6'-linked ubiquitination of NPRL2, further emphasizing its regulatory influence on specific cellular pathways, particularly those related to protein quality control.

Phosphopantothenoylcysteine Decarboxylase; PPC-DC; PPCDC; COAC

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 300 mM NaCl, 5% trehalose, 5% mannitol and 0.01% Tween 80, pH 7.4.

Room temperature in continental US; may vary elsewhere.