protein

Nucleobindin-2 Protein, Human

HY-P71177

10 μg;50 μg

170;510 USD

Nucleobindin-2 Protein, Human

proteins

E. coli

10 μg;50 μg

170;510 USD

Nucleobindin-2 protein is a calcium-binding molecule that may contribute to calcium homeostasis and act as a non-receptor guanine nucleotide exchange factor. Its interaction with the guanine nucleotide-binding protein (G protein) α subunit GNAI3 suggests its role in activating the G protein signaling pathway. Nucleobindin-2 Protein, Human is the recombinant human-derived Nucleobindin-2 protein, expressed by E. coli , with tag free.

Human

Nucleobindin-2 is a calcium-binding protein implicated in calcium homeostasis and serves as a non-receptor guanine nucleotide exchange factor, specifically interacting with and activating the guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Beyond its role in calcium dynamics, Nucleobindin-2 functions as an anorexigenic peptide, demonstrating significance in hypothalamic pathways that regulate food intake and energy homeostasis, operating in a leptin-independent manner. Additionally, this protein is suggested to have potential hypertensive effects, modulating blood pressure by directly impacting peripheral arterial resistance. It has to highlight Nucleobindin-2's diverse roles in cellular processes, spanning calcium regulation, appetite control, and potential contributions to cardiovascular physiology.

Nucleobindin-2; DNA-binding protein NEFA; Gastric cancer antigen Zg4; Prepronesfatin; Nesfatin-1; NUCB2; NEFA

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 10 mM Sodium Phosphate, pH 6.5.

Room temperature in continental US;may vary elsewhere.