RSPO1/R-spondin-1 Protein, Human (CHO, His) | MedChem Express LLC HY-P7114 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

RSPO1/R-spondin-1 Protein, Human (CHO, His)

catalog :

HY-P7114

quantity :

10 μg;50 μg;100 μg

price :

100;280;475 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7114

Product Name :

RSPO1/R-spondin-1 Protein, Human (CHO, His)

Product Type :

proteins

Host Species :

CHO

Size :

10 μg;50 μg;100 μg

List Price :

100;280;475 USD

list of Pubmed id :

375588587

Product Description :

RSPO1/R-spondin-1 Protein, Human is a secreted protein that activates Wnt signaling.

SpeciesSummary :

Human

Background :

The R-Spondin (RSpo) family of secreted proteins act as potent activators of the Wnt/ -catenin signaling pathway. R-spondin-1/RSPO1 activity critically depends on the presence of canonical Wnt ligands and LRP6 [1] . Although R-spondin-1/RSPO1 does not directly activate LRP6, R-spondin-1/RSPO1 can interfere with DKK1 function, which is to regulate the turnover of the LRP5 or LRP6 receptor and to amplify Wnt-dependent signaling [2] .

ALTnames :

rHuR-spondin-1/RSPO1; Roof plate-specific spondin-1

Purity :

Greater than 95% as determined by reducing SDS-PAGE

Buffer :

Lyophilized after extensive dialysis against PBS, pH 7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage