protein

Stathmin Protein, Human (C-His)

HY-P71121

10 μg;50 μg

120;360 USD

Stathmin Protein, Human (C-His)

proteins

E. coli

10 μg;50 μg

120;360 USD

Stathmin proteins critically regulate the microtubule filament system by actively destabilizing microtubules, inhibiting assembly, and promoting disassembly. Phosphorylation of Ser-16 is critical for axon formation during neurogenesis, highlighting its importance in neuronal development. Stathmin Protein, Human (C-His) is the recombinant human-derived Stathmin protein, expressed by E. coli , with C-6*His labeled tag.

Human

The Stathmin Protein plays a crucial role in regulating the microtubule filament system by actively destabilizing microtubules, thereby preventing their assembly and promoting disassembly. The phosphorylation of Stathmin at Ser-16 may be a key requirement for axon formation during neurogenesis, emphasizing its significance in neuronal development. Beyond its role in cellular architecture, Stathmin is implicated in the control of both learned and innate fear, indicating its potential involvement in complex behavioral processes. The protein binds to two alpha/beta-tubulin heterodimers, forming interactions critical for its microtubule-regulating functions. Additionally, Stathmin interacts with KIST, further expanding its network of molecular associations and suggesting its involvement in diverse cellular processes.

Stathmin; Leukemia-Associated Phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215; LAP18; OP18

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.