protein

PFKFB1 Protein, Human (HEK293, His)

HY-P71118

10 μg;50 μg

164;460 USD

PFKFB1 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

164;460 USD

PFKFB1 protein orchestrates the synthesis and degradation of fructose 2,6-bisphosphate, regulating cellular energy metabolism. Serving as a key enzyme, PFKFB1 modulates fructose 2,6-bisphosphate levels, impacting glycolysis and gluconeogenesis. Its dual role in both synthesis and breakdown is crucial for maintaining cellular energy homeostasis, ensuring adaptability to changing energy demands and environmental conditions. PFKFB1 Protein, Human (HEK293, His) is the recombinant human-derived PFKFB1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PFKFB1 Protein, Human (HEK293, His) is 470 a.a., with molecular weight of ~60.0 kDa.

Human

PFKFB1 protein takes center stage in the intricate orchestration of the synthesis and degradation of fructose 2,6-bisphosphate. As a key regulatory enzyme, PFKFB1 plays a crucial role in controlling cellular energy metabolism by modulating the levels of fructose 2,6-bisphosphate. This dual-function protein holds the responsibility of both synthesizing and breaking down fructose 2,6-bisphosphate, a pivotal metabolite that regulates glycolysis and gluconeogenesis. The dynamic interplay orchestrated by PFKFB1 is integral to maintaining the delicate balance of cellular energy homeostasis, influencing key metabolic pathways to ensure the cell's adaptability to varying energy demands and environmental conditions.

6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2; 6-P2ase liver isozyme; Fructose-2; 6-bisphosphatase; PFKFB1; F6PK; PFRX

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5% Trehalose, 1 mM EDTA, pH 7.8 or 20mM PB, 150mM NaCl, 5%Trehalose, 1mM EDTA, 10% Glycerol, 0.1%Tween 80, pH7.8.

Shipping with dry ice