protein

EGF Protein, Human

HY-P7109

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

30;45;70;90;130;170;220 USD

EGF Protein, Human

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

30;45;70;90;130;170;220 USD

375588581

EGF Protein is a potent epidermal growth factor that belongs to EGF-family of proteins. EGF Protein stimulates cell growth and differentiation by binding to epidermal growth factor receptor ( EGFR ) found in many human tissues, including platelets, submandibular gland (submaxillary gland) and parotid gland. EGF Protein has effects such as wound healing, anti-intestinal atrophy, anti-cancer, reducing ureteral obstruction and assisting in nerve tissue regeneration, mainly used in wound healing applications. EGF Protein (Human) is a recombinant protein with tag free that consists of 53 amino acids with three intramolecular disulfide bonds and is produced in E. coli [1],[2],[3],[4],[5],[6],[7] .

Human

Recombinant Human Epidermal Growth Factor is chemically identical to the natural material, exhibits full biological activity and is ued in wound healing applications. Recombinant Human Epidermal Growth Factor (rhEGF) stimulates proliferation of the fibroblast BALB/c3T3 cell line. Recombinant Human Epidermal Growth Factor released from hydrogels keeps its bioactivity, induces EGF receptor expression, causes proliferating cell nuclear antigen and shows therapeutic potential in enhancing diabetic wound healing [1,2] . EGF Protein (Human) promotes cellular proliferation, differentiation and survival by binding to epidermal growth factor receptor (EGFR) on the cell surface with high affinity [1] . The biological effects of salivary EGF Protein (Human) include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents [3] . EGF Protein (Human) works as an enhancer of mineralization during differentiation of mesenchymal stem cells (MSCs) derived from bone marrow. EGF Protein (Human) is capable of increasing calcium deposit formation as well as ALP and OCN gene expression, which is promising for research of an effective adjuvant to improve bone regeneration in periodontics and oral implantology [4,5] .

rHuEGF; Pro-epidermal growth factor; Urogastrone

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 10 mM Phosphate buffer, pH 7.0, 200 mM NaCl or 20 mM PB, 150 mM NaCl, pH 7.4 or 20 mM Tris, 200 mM NaCl, pH 8.0 or 50 mM Tris-HCL, 200 mM NaCl, pH 8.0 or PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.