protein

VIP Protein, Human (HEK293, His)

HY-P71061

5 μg;10 μg;50 μg

60;96;250 USD

VIP Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

60;96;250 USD

VIP is a neuropeptide that induces vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, enhances glycogenolysis, and relaxes tracheal, gastric, and gallbladder smooth muscles. PHM and PHV-related peptides also have vasodilatory properties. VIP Protein, Human (HEK293, His) is the recombinant human-derived VIP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of VIP Protein, Human (HEK293, His) is 132 a.a., with molecular weight of 17-35 kDa.

Human

VIP, a neuropeptide with diverse physiological effects, elicits vasodilation, contributing to the lowering of arterial blood pressure. It further stimulates myocardial contractility, enhances glycogenolysis, and induces relaxation in the smooth muscles of the trachea, stomach, and gall bladder. In addition to VIP, both PHM and PHV also display vasodilatory properties. Notably, PHM-27 emerges as a potent agonist of the calcitonin receptor CALCR, demonstrating efficacy comparable to that of calcitonin. These findings highlight the multifaceted actions of VIP and its related peptides in regulating cardiovascular functions and smooth muscle activity.

Vasoactive intestinal peptide; VIP; Intestinal peptide PHV-42; Peptide histidine methioninamide 27; Vasoactive intestinal polypeptide

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.