protein

PTH Protein, Human (HEK293, His)

HY-P71060

5 μg;10 μg;50 μg

46;80;220 USD

PTH Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

46;80;220 USD

PTH Protein, or parathyroid hormone, raises calcium levels by dissolving bone salts and inhibiting kidney excretion. It also stimulates [1-14C]-2-deoxy-D-glucose transport and glycogen synthesis in osteoblastic cells, interacting with the PTH1R receptor and binding to its N-terminal extracellular domain for these effects. PTH Protein, Human (HEK293, His) is the recombinant human-derived PTH protein, expressed by HEK293 , with N-8*His labeled tag. The total length of PTH Protein, Human (HEK293, His) is 84 a.a., with molecular weight of ~15 kDa.

Human

PTH, or parathyroid hormone, functions to increase calcium levels by facilitating the dissolution of bone salts and inhibiting their excretion by the kidneys. Additionally, it stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and promotes glycogen synthesis in osteoblastic cells. PTH achieves these effects through its interaction with the PTH1R receptor, specifically binding to the N-terminal extracellular domain of the receptor.

Parathyroid hormone; PTH; Parathormone; Parathyrin; PTH

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.