protein

PDYN Protein, Human (HEK293, His)

HY-P71058

10 μg;50 μg

150;420 USD

PDYN Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

150;420 USD

The PDYN protein, or prodynorphin, regulates Leu-enkephalins, mimicking opiate drug effects and impacting pain perception and stress responses. Dynorphin peptides, like Dynorphin A(1-13), uniquely regulate the kappa opioid receptor, with A(1-13) being exceptionally potent—700 times stronger than Leu-enkephalin—displaying typical opioid activity. PDYN Protein, Human (HEK293, His) is the recombinant human-derived PDYN protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDYN Protein, Human (HEK293, His) is 234 a.a., with molecular weight of ~35.0 kDa.

Human

The PDYN protein, also known as prodynorphin, is associated with Leu-enkephalins, which compete with and emulate the effects of opiate drugs. These peptides play a pivotal role in various physiological functions, including pain perception and responses to stress. Additionally, dynorphin peptides, such as Dynorphin A(1-13), exhibit differential regulation of the kappa opioid receptor. Notably, Dynorphin A(1-13) demonstrates typical opioid activity and is remarkably more potent, being 700 times stronger than Leu-enkephalin.

ADCA; PENKB; SCA23; PDYN; Dynorphin B; Big Dyn

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.